Anti-CAV3 antibody (1-151) (STJ110389) STJ110389 上海玉博生物科技有限公司

Anti-CAV3 antibody (1-151) (STJ110389)

简单介绍

Anti-CAV3 antibody (1-151) (STJ110389)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Caveolin-3 (1-151) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CAV3
Gene ID:	859
Uniprot ID:	CAV3_HUMAN
Immunogen Region:	1-151
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-151 of human Caveolin-3 (NP_001225.1).
Immunogen Sequence:	MMAEEHTDLEAQIVKDIHCK EIDLVNRDPKNINEDIVKVD FEDVIAEPVGTYSFDGVWKV SYTTFTVSKYWCYRLLSTLL GVPLALLWGFLFACISFCHI WAVVPCIKSYLIEIQCISHI YSLCIRTFCNPLFAALGQVC SSIKVVLRKEV

Tissue Specificity	Expressed predominantly in muscle.
Post Translational Modifications	Sumoylation with SUMO3 by PIAS4 may reduce agonist-induced internalization and desensitization of adrenergic receptor ABRD2.
Function	May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae.
Protein Name	Caveolin-3 M-Caveolin
Database Links	Reactome: R-HSA-445355
Cellular Localisation	Golgi Apparatus Membrane Peripheral Membrane Protein Cell Membrane Membrane Caveola Sarcolemma Potential Hairpin-Like Structure In The Membrane Membrane Protein Of Caveolae
Alternative Antibody Names	Anti-Caveolin-3 antibody Anti-M-Caveolin antibody Anti-CAV3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

��系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录