Anti-CAVIN1 antibody (90-170 aa) (STJ190168) STJ190168 上海玉博生物科技有限公司

Anti-CAVIN1 antibody (90-170 aa) (STJ190168)

简单介绍

Anti-CAVIN1 antibody (90-170 aa) (STJ190168)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Caveolae-associated protein 1 (90-170 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CAVIN1
Gene ID:	284119
Uniprot ID:	CAVN1_HUMAN
Immunogen Region:	90-170 aa
Specificity:	PTRF Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 90-170

Function	Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues. Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1). Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop. Dissociates transcription complexes paused by DNA-bound TTF1, thereby releasing both RNA polymerase I and pre-RNA from the template. The caveolae biogenesis pathway is required for the secretion of proteins such as GASK1A.
Protein Name	Caveolae-Associated Protein 1 Cavin-1 Polymerase I And Transcript Release Factor
Database Links	Reactome: R-HSA-73863 Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106
Cellular Localisation	Membrane Caveola Cell Membrane Microsome Endoplasmic Reticulum Cytoplasm Cytosol Mitochondrion Nucleus Translocates To The Cytoplasm From The Caveolae Upon Insulin Stimulation Colocalizes With Cav1 In Lipid Rafts In Adipocytes Localizes In The Caveolae In A Caveolin-Dependent Manner
Alternative Antibody Names	Anti-Caveolae-Associated Protein 1 antibody Anti-Cavin-1 antibody Anti-Polymerase I And Transcript Release Factor antibody Anti-CAVIN1 antibody Anti-PTRF antibody Anti-FKSG13 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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