Anti-CBR1 antibody (1-277) (STJ11100047) STJ11100047 上海玉博生物科技有限公司

Anti-CBR1 antibody (1-277) (STJ11100047)

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产品名称：Anti-CBR1 antibody (1-277) (STJ11100047)
产品型号：STJ11100047
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CBR1 antibody (1-277) (STJ11100047)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CBR1 (1-277) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CBR1
Gene ID:	873
Uniprot ID:	CBR1_HUMAN
Immunogen Region:	1-277
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human CBR1 (NP_001748.1).
Immunogen Sequence:	MSSGIHVALVTGGNKGIGLA IVRDLCRLFSGDVVLTARDV TRGQAAVQQLQAEGLSPRFH QLDIDDLQSIRALRDFLRKE YGGLDVLVNNAGIAFKVADP TPFHIQAEVTMKTNFFGTRD VCTELLPLIKPQGRVVNVSS IMSVRALKSCSPELQQKFRS ETITEEELVGLMNKFVEDTK KGVHQKEGWPSSAYGVTKIG VTVLSRIHARKLSEQRKGDK ILLNACCPGWVRTDMAGPK

Tissue Specificity	Expressed in kidney (at protein level).
Function	NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. In addition, participates in the glucocorticoid metabolism by catalyzing the NADPH-dependent cortisol/corticosterone into 20beta-dihydrocortisol (20b-DHF) or 20beta-corticosterone (20b-DHB), which are weak agonists of NR3C1 and NR3C2 in adipose tissue.
Protein Name	Carbonyl Reductase Nadph 1 15-Hydroxyprostaglandin Dehydrogenase Nadp(+ 20-Beta-Hydroxysteroid Dehydrogenase Alcohol Dehydrogenase Nad(P+ Cbr1 Nadph-Dependent Carbonyl Reductase 1 Prostaglandin 9-Ketoreductase Pg-9-Kr Prostaglandin-E(2 9-Reductase Short Chain Dehydrogenase/Reductase Family 21c Member 1
Database Links	Reactome: R-HSA-2162123
Cellular Localisation	Cytoplasm
Alternative Antibody Names	Anti-Carbonyl Reductase Nadph 1 antibody Anti-15-Hydroxyprostaglandin Dehydrogenase Nadp(+ antibody Anti-20-Beta-Hydroxysteroid Dehydrogenase antibody Anti-Alcohol Dehydrogenase Nad(P+ Cbr1 antibody Anti-Nadph-Dependent Carbonyl Reductase 1 antibody Anti-Prostaglandin 9-Ketoreductase antibody Anti-Pg-9-Kr antibody Anti-Prostaglandin-E(2 9-Reductase antibody Anti-Short Chain Dehydrogenase/Reductase Family 21c Member 1 antibody Anti-CBR1 antibody Anti-CBR antibody Anti-CRN antibody Anti-SDR21C1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CBR1 antibody (1-277) (STJ11100047)