Anti-ATXN2 antibody (1250-1331) (STJ119084) STJ119084 上海玉博生物科技有限公司

Anti-ATXN2 antibody (1250-1331) (STJ119084)

简单介绍

Anti-ATXN2 antibody (1250-1331) (STJ119084)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ATXN2 (1250-1331) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ATXN2
Gene ID:	6311
Uniprot ID:	ATX2_HUMAN
Immunogen Region:	1250-1331
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 1250-1331 of human ATXN2 (NP_002964.3).
Immunogen Sequence:	HVQSGMVPSHPTAHAPMMLM TTQPPGGPQAALAQSALQPI PVSTTAHFPYMTHPSVQAHH QQQL

Tissue Specificity	Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.
Function	Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.
Protein Name	Ataxin-2 Spinocerebellar Ataxia Type 2 Protein Trinucleotide Repeat-Containing Gene 13 Protein
Cellular Localisation	Cytoplasm
Alternative Antibody Names	Anti-Ataxin-2 antibody Anti-Spinocerebellar Ataxia Type 2 Protein antibody Anti-Trinucleotide Repeat-Containing Gene 13 Protein antibody Anti-ATXN2 antibody Anti-ATX2 antibody Anti-SCA2 antibody Anti-TNRC13 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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