Anti-CBX5 antibody (41-90 aa) (STJ93588) STJ93588 上海玉博生物科技有限公司

Anti-CBX5 antibody (41-90 aa) (STJ93588)

简单介绍

Anti-CBX5 antibody (41-90 aa) (STJ93588)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Chromobox protein homolog 5 (41-90 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CBX5
Gene ID:	23468
Uniprot ID:	CBX5_HUMAN
Immunogen Region:	41-90 aa
Specificity:	HP1 Alpha Polyclonal Antibody detects endogenous levels of HP1 Alpha protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human CBX5 at the amino acid range 41-90

Function	Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Protein Name	Chromobox Protein Homolog 5 Antigen P25 Heterochromatin Protein 1 Homolog Alpha Hp1 Alpha
Database Links	Reactome: R-HSA-4551638 Reactome: R-HSA-8953750 Reactome: R-HSA-983231
Cellular Localisation	Nucleus Chromosome Centromere Colocalizes With Hnrnpu In The Nucleus Component Of Centromeric And Pericentromeric Heterochromatin Associates With Chromosomes During Mitosis Associates Specifically With Chromatin During Metaphase And Anaphase Localizes To Sites Of Dna Damage
Alternative Antibody Names	Anti-Chromobox Protein Homolog 5 antibody Anti-Antigen P25 antibody Anti-Heterochromatin Protein 1 Homolog Alpha antibody Anti-Hp1 Alpha antibody Anti-CBX5 antibody Anti-HP1A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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