Anti-CBX6 antibody (10-59 aa) (STJ92064) STJ92064 上海玉博生物科技有限公司

Anti-CBX6 antibody (10-59 aa) (STJ92064)

简单介绍

Anti-CBX6 antibody (10-59 aa) (STJ92064)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Chromobox protein homolog 6 (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CBX6
Gene ID:	23466
Uniprot ID:	CBX6_HUMAN
Immunogen Region:	10-59 aa
Specificity:	CBX6 Polyclonal Antibody detects endogenous levels of CBX6 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human CBX6 at the amino acid range 10-59

Function	Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones.it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin. Recruitment to chromatin might occur in an H3K27me3-independent fashion. May have a PRC1-independent function in embryonic stem cells.
Protein Name	Chromobox Protein Homolog 6
Database Links	Reactome: R-HSA-2559580 Reactome: R-HSA-8939243 Reactome: R-HSA-8943724
Cellular Localisation	Nucleus Chromosome Uniformely Distributed In The Nucleoplasm Localizes To The Inactivated X Chromosome In Females
Alternative Antibody Names	Anti-Chromobox Protein Homolog 6 antibody Anti-CBX6 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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