Anti-CCL17 antibody (450-550) (STJ11104710) STJ11104710 上海玉博生物科技有限公司

Anti-CCL17 antibody (450-550) (STJ11104710)

简单介绍

Anti-CCL17 antibody (450-550) (STJ11104710)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-C-C Motif Chemokine 17 (450-550) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCL17
Gene ID:	6361
Uniprot ID:	CCL17_HUMAN
Immunogen Region:	450-550
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 450-550 of human AAK1 (NP_055726.4).
Immunogen Sequence:	AQGLPAQAQATPQHQQQLFL KQQQQQQQPPPAQQQPAGTF YQQQQAQTQQFQAVHPATQK PAIAQFPVVSQGGSQQQLMQ NFYQQQQQQQQQQQQQQLAT A

Tissue Specificity	Constitutively expressed in thymus. Detected at lower levels in the lung, colon and small intestine. Expressed in stimulated peripheral blood mononuclear cells, but not in resting cells.
Function	Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound.
Protein Name	C-C Motif Chemokine 17 Cc Chemokine Tarc Small-Inducible Cytokine A17 Thymus And Activation-Regulated Chemokine
Database Links	Reactome: R-HSA-380108
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-C-C Motif Chemokine 17 antibody Anti-Cc Chemokine Tarc antibody Anti-Small-Inducible Cytokine A17 antibody Anti-Thymus And Activation-Regulated Chemokine antibody Anti-CCL17 antibody Anti-SCYA17 antibody Anti-TARC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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