Anti-CCL19 antibody (22-95) (STJ119251) STJ119251 上海玉博生物科技有限公司

Anti-CCL19 antibody (22-95) (STJ119251)

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产品名称：Anti-CCL19 antibody (22-95) (STJ119251)
产品型号：STJ119251
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CCL19 antibody (22-95) (STJ119251)

产品描述

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CCL19 (22-95) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IF/ICC 1:50-1:100
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCL19
Gene ID:	6363
Uniprot ID:	CCL19_HUMAN
Immunogen Region:	22-95
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 22-95 of human CCL19 (NP_006265.1).
Immunogen Sequence:	GTNDAEDCCLSVTQKPIPGY IVRNFHYLLIKDGCRVPAVV FTTLRGRQLCAPPDQPWVER IIQRLQRTSAKMKR

Tissue Specificity	Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
Function	May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name	C-C Motif Chemokine 19 Beta-Chemokine Exodus-3 Ck Beta-11 Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine Ebi1 Ligand Chemokine Elc Macrophage Inflammatory Protein 3 Beta Mip-3-Beta Small-Inducible Cytokine A19
Database Links	Reactome: R-HSA-380108 Reactome: R-HSA-418594 Reactome: R-HSA-6783783
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-C-C Motif Chemokine 19 antibody Anti-Beta-Chemokine Exodus-3 antibody Anti-Ck Beta-11 antibody Anti-Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine antibody Anti-Ebi1 Ligand Chemokine antibody Anti-Elc antibody Anti-Macrophage Inflammatory Protein 3 Beta antibody Anti-Mip-3-Beta antibody Anti-Small-Inducible Cytokine A19 antibody Anti-CCL19 antibody Anti-ELC antibody Anti-MIP3B antibody Anti-SCYA19 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CCL19 antibody (22-95) (STJ119251)