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Anti-CCL2 antibody (22-99) [S4938RM] (STJ11104938)

Anti-CCL2 antibody (22-99) [S4938RM] (STJ11104938)
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  • 产品名称:Anti-CCL2 antibody (22-99) [S4938RM] (STJ11104938)
  • 产品型号:STJ11104938
  • 产品展商:ST john's laboratory
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简单介绍
Anti-CCL2 antibody (22-99) [S4938RM] (STJ11104938)
产品描述
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-C-C Motif Chemokine 2 (22-99) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S4938RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:2000-1:9000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCL2
Gene ID: 6347
Uniprot ID: CCL2_HUMAN
Immunogen Region: 22-99
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-99 of human CCL2/MCP-1 (NP_002973.1).
Immunogen Sequence: LAQPDAINAPVTCCYNFTNR KISVQRLASYRRITSSKCPK EAVIFKTIVAKEICADPKQK WVQDSMDHLDKQTQTPKT
Tissue Specificity Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level). Expressed in monocytes.
Post Translational Modifications Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. N-Glycosylated.
Function Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Protein Name C-C Motif Chemokine 2
Hc11
Monocyte Chemoattractant Protein 1
Monocyte Chemotactic And Activating Factor
Mcaf
Monocyte Chemotactic Protein 1
Mcp-1
Monocyte Secretory Protein Je
Small-Inducible Cytokine A2
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-380994
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-C Motif Chemokine 2 antibody
Anti-Hc11 antibody
Anti-Monocyte Chemoattractant Protein 1 antibody
Anti-Monocyte Chemotactic And Activating Factor antibody
Anti-Mcaf antibody
Anti-Monocyte Chemotactic Protein 1 antibody
Anti-Mcp-1 antibody
Anti-Monocyte Secretory Protein Je antibody
Anti-Small-Inducible Cytokine A2 antibody
Anti-CCL2 antibody
Anti-MCP1 antibody
Anti-SCYA2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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