Anti-CCL21 antibody (24-134) (STJ22930) STJ22930 上海玉博生物科技有限公司

Anti-CCL21 antibody (24-134) (STJ22930)

简单介绍

Anti-CCL21 antibody (24-134) (STJ22930)

产品描述

Host:	Rabbit
Applications:	IHC
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CCL21 (24-134) is suitable for use in Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	IHC-P 1:50-1:100
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCL21
Gene ID:	6366
Uniprot ID:	CCL21_HUMAN
Immunogen Region:	24-134
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 24-134 of human CCL21 (NP_002980.1).
Immunogen Sequence:	SDGGAQDCCLKYSQRKIPAK VVRSYRKQEPSLGCSIPAIL FLPRKRSQAELCADPKELWV QQLMQHLDKTPSPQKPAQGC RKDRGASKTGKKGKGSKGCK RTERSQTPKGP

Tissue Specificity	Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen.
Function	Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name	C-C Motif Chemokine 21 6ckine Beta-Chemokine Exodus-2 Secondary Lymphoid-Tissue Chemokine Slc Small-Inducible Cytokine A21
Database Links	Reactome: R-HSA-380108 Reactome: R-HSA-418594
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-C-C Motif Chemokine 21 antibody Anti-6ckine antibody Anti-Beta-Chemokine Exodus-2 antibody Anti-Secondary Lymphoid-Tissue Chemokine antibody Anti-Slc antibody Anti-Small-Inducible Cytokine A21 antibody Anti-CCL21 antibody Anti-SCYA21 antibody Anti-UNQ784 antibody Anti-PRO1600 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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