Human ILK-1 (Integrin Linked Kinase 1) Sandwich ELISA Kit (STJE0009993) STJE0009993 上海玉博生物科技有限公司

Human ILK-1 (Integrin Linked Kinase 1) Sandwich ELISA Kit (STJE0009993)

简单介绍

Human ILK-1 (Integrin Linked Kinase 1) Sandwich ELISA Kit (STJE0009993)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	33.5pg/mL
Detection Limit:	78.1-5000pg/mL
Short Description:	This ILK-1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	ILK
Gene ID:	3611
Uniprot ID:	ILK_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.
Post Translational Modifications	Autophosphorylated on serine residues.
Function	Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Regulates cell motility by forming a complex with PARVB. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
Protein Name	Integrin-Linked Protein Kinase 59 Kda Serine/Threonine-Protein Kinase Beta-Integrin-Linked Kinase Ilk-1 Ilk-2 P59ilk
Database Links	Reactome: R-HSA-446343 Reactome: R-HSA-446353
Cellular Localisation	Cell Junction Focal Adhesion Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Cell Projection Lamellipodium Cytoplasm Myofibril Sarcomere
Alternative ELISA Names	Integrin-Linked Protein Kinase ELISA kit 59 Kda Serine/Threonine-Protein Kinase ELISA kit Beta-Integrin-Linked Kinase ELISA kit Ilk-1 ELISA kit Ilk-2 ELISA kit P59ilk ELISA kit ILK ELISA kit ILK1 ELISA kit ILK2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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