Anti-CCNA1 antibody (1-230) (STJ27598) STJ27598 上海玉博生物科技有限公司

Anti-CCNA1 antibody (1-230) (STJ27598)

简单介绍

Anti-CCNA1 antibody (1-230) (STJ27598)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CCNA1 (1-230) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCNA1
Gene ID:	8900
Uniprot ID:	CCNA1_HUMAN
Immunogen Region:	1-230
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CCNA1 (NP_001104515.1).
Immunogen Sequence:	METGFPAIMYPGSFIGGWGE EYLSWEGPGLPDFVFQQPVE SEAMHCSNPKSGVVLATVAR GPDACQILTRAPLGQDPPQR TVLGLLTANGQYRRTCGQGI TRIRCYSGSENAFPPAGKKA LPDCGVQEPPKQGFDIYMDE LEQGDRDSCSVREGMAFEDV YEVDTGTLKSDLHFLLDFNT VSPMLVDSSLLSQSEDISSL GTDVINVTEYAEEIYQYLRE AEIRHRPKAH

Tissue Specificity	Very high levels in testis and very low levels in brain. Also found in myeloid leukemia cell lines.
Post Translational Modifications	Polyubiquitinated via 'Lys-11'-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.
Function	May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
Protein Name	Cyclin-A1
Database Links	Reactome: R-HSA-1538133 Reactome: R-HSA-170145 Reactome: R-HSA-171319 Reactome: R-HSA-174184 Reactome: R-HSA-176408 Reactome: R-HSA-187577 Reactome: R-HSA-2559582 Reactome: R-HSA-2559586 Reactome: R-HSA-5689880 Reactome: R-HSA-5693607 Reactome: R-HSA-6804116 Reactome: R-HSA-6804756 Reactome: R-HSA-6804757 Reactome: R-HSA-68911 Reactome: R-HSA-68949 Reactome: R-HSA-69017 Reactome: R-HSA-69205 Reactome: R-HSA-69273 Reactome: R-HSA-69563 Reactome: R-HSA-69656
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Cyclin-A1 antibody Anti-CCNA1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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