Anti-CCNA1 antibody (350-450) (STJ116740) STJ116740 上海玉博生物科技有限公司

Anti-CCNA1 antibody (350-450) (STJ116740)

简单介绍

Anti-CCNA1 antibody (350-450) (STJ116740)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CCNA1 (350-450) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCNA1
Gene ID:	8900
Uniprot ID:	CCNA1_HUMAN
Immunogen Region:	350-450
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 350-450 of human CCNA1 (NP_001104515.1).
Immunogen Sequence:	YLRRQGVCVRTENLAKYVAE LSLLEADPFLKYLPSLIAAA AFCLANYTVNKHFWPETLAA FTGYSLSEIVPCLSELHKAY LDIPHRPQQAIREKYKASKY L

Tissue Specificity	Very high levels in testis and very low levels in brain. Also found in myeloid leukemia cell lines.
Post Translational Modifications	Polyubiquitinated via 'Lys-11'-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.
Function	May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
Protein Name	Cyclin-A1
Database Links	Reactome: R-HSA-1538133 Reactome: R-HSA-170145 Reactome: R-HSA-171319 Reactome: R-HSA-174184 Reactome: R-HSA-176408 Reactome: R-HSA-187577 Reactome: R-HSA-2559582 Reactome: R-HSA-2559586 Reactome: R-HSA-5689880 Reactome: R-HSA-5693607 Reactome: R-HSA-6804116 Reactome: R-HSA-6804756 Reactome: R-HSA-6804757 Reactome: R-HSA-68911 Reactome: R-HSA-68949 Reactome: R-HSA-69017 Reactome: R-HSA-69205 Reactome: R-HSA-69273 Reactome: R-HSA-69563 Reactome: R-HSA-69656
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Cyclin-A1 antibody Anti-CCNA1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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