Anti-CCNA2 antibody (1-200) (STJ117230) STJ117230 上海玉博生物科技有限公司

Anti-CCNA2 antibody (1-200) (STJ117230)

简单介绍

Anti-CCNA2 antibody (1-200) (STJ117230)

产品描述

Host:	Rabbit
Applications:	IF
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CCNA2 (1-200) is suitable for use in Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	IF 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCNA2
Gene ID:	890
Uniprot ID:	CCNA2_HUMAN
Immunogen Region:	1-200
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CCNA2 (NP_001228.1).
Immunogen Sequence:	MLGNSAPGPATREAGSALLA LQQTALQEDQENINPEKAAP VQQPRTRAALAVLKSGNPRG LAQQQRPKTRRVAPLKDLPV NDEHVTVPPWKANSKQPAFT IHVDEAEKEAQKKPAESQKI EREDALAFNSAISLPGPRKP LVPLDYPMDGSFESPHTMDM SIVLEDEKPVSVNEVPDYHE DIHTYLREMEVKCKPKVGYM

Post Translational Modifications	Polyubiquitinated via 'Lys-11'-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.
Function	Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.
Protein Name	Cyclin-A2 Cyclin-A Cyclin A
Database Links	Reactome: R-HSA-1362300 Reactome: R-HSA-1538133 Reactome: R-HSA-170145 Reactome: R-HSA-171319 Reactome: R-HSA-174184 Reactome: R-HSA-176408 Reactome: R-HSA-187577 Reactome: R-HSA-2559582 Reactome: R-HSA-2559586 Reactome: R-HSA-5689880 Reactome: R-HSA-5693607 Reactome: R-HSA-6804116 Reactome: R-HSA-6804756 Reactome: R-HSA-6804757 Reactome: R-HSA-68911 Reactome: R-HSA-68949 Reactome: R-HSA-69017 Reactome: R-HSA-69273 Reactome: R-HSA-69563 Reactome: R-HSA-69656
Cellular Localisation	Nucleus Cytoplasm Exclusively Nuclear During Interphase Detected In The Nucleus And The Cytoplasm At Prophase Cytoplasmic When Associated With Scaper
Alternative Antibody Names	Anti-Cyclin-A2 antibody Anti-Cyclin-A antibody Anti-Cyclin A antibody Anti-CCNA2 antibody Anti-CCN1 antibody Anti-CCNA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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