Human IRAK3 (Interleukin 1 Receptor Associated Kinase 3) Sandwich ELISA Kit (STJE0010048) STJE0010048 上海玉博生物科技有限公司

Human IRAK3 (Interleukin 1 Receptor Associated Kinase 3) Sandwich ELISA Kit (STJE0010048)

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产品名称：Human IRAK3 (Interleukin 1 Receptor Associated Kinase 3) Sandwich ELISA Kit (STJE0010048)
产品型号：STJE0010048
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human IRAK3 (Interleukin 1 Receptor Associated Kinase 3) Sandwich ELISA Kit (STJE0010048)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.23ng/mL
Detection Limit:	0.781-50ng/mL
Short Description:	This IRAK3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	IRAK3
Gene ID:	11213
Uniprot ID:	IRAK3_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Expressed in eosinophils, dendritic cells and/or monocytes (at protein level). Expressed predominantly in peripheral blood lymphocytes.
Post Translational Modifications
Function	Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors. Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells.
Protein Name	Interleukin-1 Receptor-Associated Kinase 3 Irak-3 Il-1 Receptor-Associated Kinase M Irak-M Inactive Il-1 Receptor-Associated Kinase 3
Database Links	Reactome: R-HSA-166058 Reactome: R-HSA-9020702
Cellular Localisation	Cytoplasm Nucleus In Dendritic Cells Translocates Into The Nucleus Upon Il33 Stimulation
Alternative ELISA Names	Interleukin-1 Receptor-Associated Kinase 3 ELISA kit Irak-3 ELISA kit Il-1 Receptor-Associated Kinase M ELISA kit Irak-M ELISA kit Inactive Il-1 Receptor-Associated Kinase 3 ELISA kit IRAK3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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