Human IRF9 (Interferon Regulatory Factor 9) Sandwich ELISA Kit Ready-To-Use (STJE0016447) STJE0016447 上海玉博生物科技有限公司

Human IRF9 (Interferon Regulatory Factor 9) Sandwich ELISA Kit Ready-To-Use (STJE0016447)

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产品名称：Human IRF9 (Interferon Regulatory Factor 9) Sandwich ELISA Kit Ready-To-Use (STJE0016447)
产品型号：STJE0016447
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human IRF9 (Interferon Regulatory Factor 9) Sandwich ELISA Kit Ready-To-Use (STJE0016447)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.042ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This IRF9 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	IRF9
Gene ID:	10379
Uniprot ID:	IRF9_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications	(Microbial infection) Ubiquitinated by Herpes simplex virus 2 E3 ubiquitin ligase ICP22.
Function	Transcription factor that plays an essential role in anti-viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Protein Name	Interferon Regulatory Factor 9 Irf-9 Ifn-Alpha-Responsive Transcription Factor Subunit Isgf3 P48 Subunit Interferon-Stimulated Gene Factor 3 Gamma Isgf-3 Gamma Transcriptional Regulator Isgf3 Subunit Gamma
Database Links	Reactome: R-HSA-877300 Reactome: R-HSA-909733
Cellular Localisation	Cytoplasm Nucleus Translocated Into The Nucleus Upon Activation By Ifn-Alpha/Beta
Alternative ELISA Names	Interferon Regulatory Factor 9 ELISA kit Irf-9 ELISA kit Ifn-Alpha-Responsive Transcription Factor Subunit ELISA kit Isgf3 P48 Subunit ELISA kit Interferon-Stimulated Gene Factor 3 Gamma ELISA kit Isgf-3 Gamma ELISA kit Transcriptional Regulator Isgf3 Subunit Gamma ELISA kit IRF9 ELISA kit ISGF3G ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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