Anti-CCNH antibody (1-100) [S4592RM] (STJ11104592) STJ11104592 上海玉博生物科技有限公司

Anti-CCNH antibody (1-100) [S4592RM] (STJ11104592)

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产品名称：Anti-CCNH antibody (1-100) [S4592RM] (STJ11104592)
产品型号：STJ11104592
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CCNH antibody (1-100) [S4592RM] (STJ11104592)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-Cyclin-H (1-100) is suitable for use in Western Blot research applications.

Clonality:	Monoclonal
Clone ID:	S4592RM
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCNH
Gene ID:	902
Uniprot ID:	CCNH_HUMAN
Immunogen Region:	1-100
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cyclin H (P51946).
Immunogen Sequence:	MYHNSSQKRHWTFSSEEQLA RLRADANRKFRCKAVANGKV LPNDPVFLEPHEEMTLCKYY EKRLLEFCSVFKPAMPRSVV GTACMYFKRFYLNNSVMEYH

Function	Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Protein Name	Cyclin-H Mo15-Associated Protein P34 P37
Database Links	Reactome: R-HSA-112382 Reactome: R-HSA-113418 Reactome: R-HSA-167152 Reactome: R-HSA-167158 Reactome: R-HSA-167160 Reactome: R-HSA-167161 Reactome: R-HSA-167162 Reactome: R-HSA-167172 Reactome: R-HSA-167200 Reactome: R-HSA-167246 Reactome: R-HSA-427413 Reactome: R-HSA-5696395 Reactome: R-HSA-674695 Reactome: R-HSA-6781823 Reactome: R-HSA-6781827 Reactome: R-HSA-6782135 Reactome: R-HSA-6782210 Reactome: R-HSA-6796648 Reactome: R-HSA-69202 Reactome: R-HSA-69231 Reactome: R-HSA-69273 Reactome: R-HSA-69656 Reactome: R-HSA-72086 Reactome: R-HSA-73762 Reactome: R-HSA-73772 Reactome: R-HSA-73776 Reactome: R-HSA-73779 Reactome: R-HSA-73863 Reactome: R-HSA-75953 Reactome: R-HSA-75955 Reactome: R-HSA-76042 Reactome: R-HSA-77075 Reactome: R-HSA-8939236
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Cyclin-H antibody Anti-Mo15-Associated Protein antibody Anti-P34 antibody Anti-P37 antibody Anti-CCNH antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CCNH antibody (1-100) [S4592RM] (STJ11104592)