Anti-BACH2 antibody (250-330 aa) (STJ191801) STJ191801 上海玉博生物科技有限公司

Anti-BACH2 antibody (250-330 aa) (STJ191801)

简单介绍

Anti-BACH2 antibody (250-330 aa) (STJ191801)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Transcription regulator protein BACH2 (250-330 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BACH2
Gene ID:	60468
Uniprot ID:	BACH2_HUMAN
Immunogen Region:	250-330 aa
Specificity:	BACH2 Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 250-330

Post Translational Modifications	Phosphorylation at Ser-521 downstream of the PI-3K pathway promotes nuclear export. The reversible disulfide bond may provide a mechanism to regulate the activity in oxidative stress responses.
Function	Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Plays an important role in coordinating transcription activation and repression by MAFK. Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1. Positively regulates the nuclear import of actin. Is a key regulator of adaptive immunity, crucial for the maintenance of regulatory T-cell function and B-cell maturation.
Protein Name	Transcription Regulator Protein Bach2 Btb And Cnc Homolog 2
Cellular Localisation	Cytoplasm Nucleus Nucleocytoplasmic Shuttling Is Controlled By Phosphorylation
Alternative Antibody Names	Anti-Transcription Regulator Protein Bach2 antibody Anti-Btb And Cnc Homolog 2 antibody Anti-BACH2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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