Human JAM1 (Junctional Adhesion Molecule 1) Sandwich ELISA Kit Ready-To-Use (STJE0016505) STJE0016505 上海玉博生物科技有限公司

Human JAM1 (Junctional Adhesion Molecule 1) Sandwich ELISA Kit Ready-To-Use (STJE0016505)

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产品名称：Human JAM1 (Junctional Adhesion Molecule 1) Sandwich ELISA Kit Ready-To-Use (STJE0016505)
产品型号：STJE0016505
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human JAM1 (Junctional Adhesion Molecule 1) Sandwich ELISA Kit Ready-To-Use (STJE0016505)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.133ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This JAM1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	F11R
Gene ID:	50848
Uniprot ID:	JAM1_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Expressed in endothelium, epithelium and leukocytes (at protein level).
Post Translational Modifications	N-glycosylated. (Microbial infection) Cleaved by H.pylori virulence factor PqqE. Cleavage leads to altered tight junction functions.
Function	Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation. (Microbial infection) Acts as a receptor for Mammalian reovirus sigma-1. (Microbial infection) Acts as a receptor for Human Rotavirus strain Wa.
Protein Name	Junctional Adhesion Molecule A Jam-A Junctional Adhesion Molecule 1 Jam-1 Platelet F11 Receptor Platelet Adhesion Molecule 1 Pam-1 Cd Antigen Cd321
Database Links	Reactome: R-HSA-202733 Reactome: R-HSA-216083 Reactome: R-HSA-2173791 Reactome: R-HSA-420029
Cellular Localisation	Cell Junction Tight Junction Cell Membrane Single-Pass Type I Membrane Protein Localized At Tight Junctions Of Both Epithelial And Endothelial Cells
Alternative ELISA Names	Junctional Adhesion Molecule A ELISA kit Jam-A ELISA kit Junctional Adhesion Molecule 1 ELISA kit Jam-1 ELISA kit Platelet F11 Receptor ELISA kit Platelet Adhesion Molecule 1 ELISA kit Pam-1 ELISA kit Cd Antigen Cd321 ELISA kit F11R ELISA kit JAM1 ELISA kit JCAM ELISA kit UNQ264 ELISA kit PRO301 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human JAM1 (Junctional Adhesion Molecule 1) Sandwich ELISA Kit Ready-To-Use (STJE0016505)