Human JUP (Junction Plakoglobin) Sandwich ELISA Kit Ready-To-Use (STJE0016516) STJE0016516 上海玉博生物科技有限公司

Human JUP (Junction Plakoglobin) Sandwich ELISA Kit Ready-To-Use (STJE0016516)

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产品名称：Human JUP (Junction Plakoglobin) Sandwich ELISA Kit Ready-To-Use (STJE0016516)
产品型号：STJE0016516
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human JUP (Junction Plakoglobin) Sandwich ELISA Kit Ready-To-Use (STJE0016516)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.054ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This JUP Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	JUP
Gene ID:	3728
Uniprot ID:	PLAK_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Expressed in the heart (at protein level).
Post Translational Modifications	May be phosphorylated by FER.
Function	Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
Protein Name	Junction Plakoglobin Catenin Gamma Desmoplakin Iii Desmoplakin-3
Database Links	Reactome: R-HSA-418990 Reactome: R-HSA-5218920 Reactome: R-HSA-6798695 Reactome: R-HSA-6805567 Reactome: R-HSA-6809371 Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106 Reactome: R-HSA-9013148 Reactome: R-HSA-9013406 Reactome: R-HSA-9013407 Reactome: R-HSA-9013409 Reactome: R-HSA-9762292 Reactome: R-HSA-9764302 Reactome: R-HSA-9833576
Cellular Localisation	Cell Junction Adherens Junction Desmosome Cytoplasm Cytoskeleton Membrane Peripheral Membrane Protein Cytoplasmic In A Soluble And Membrane-Associated Form
Alternative ELISA Names	Junction Plakoglobin ELISA kit Catenin Gamma ELISA kit Desmoplakin Iii ELISA kit Desmoplakin-3 ELISA kit JUP ELISA kit CTNNG ELISA kit DP3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human JUP (Junction Plakoglobin) Sandwich ELISA Kit Ready-To-Use (STJE0016516)