Human KIF14 (Kinesin Family, Member 14) Sandwich ELISA Kit Ready-To-Use (STJE0016537) STJE0016537 上海玉博生物科技有限公司

Human KIF14 (Kinesin Family, Member 14) Sandwich ELISA Kit Ready-To-Use (STJE0016537)

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产品名称：Human KIF14 (Kinesin Family, Member 14) Sandwich ELISA Kit Ready-To-Use (STJE0016537)
产品型号：STJE0016537
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human KIF14 (Kinesin Family, Member 14) Sandwich ELISA Kit Ready-To-Use (STJE0016537)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.126ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This KIF14 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	KIF14
Gene ID:	9928
Uniprot ID:	KIF14_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity. Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis. During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively. Regulates cell growth through regulation of cell cycle progression and cytokinesis. During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1. During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division. Also is required for chromosome congression and alignment during mitotic cell cycle process. Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules.
Protein Name	Kinesin-Like Protein Kif14
Database Links	Reactome: R-HSA-5625900 Reactome: R-HSA-9696270 Reactome: R-HSA-9696273
Cellular Localisation	Nucleus Cytoplasm Cytoskeleton Spindle Midbody Nuclear Localization Observed During Interphase Nuclear Localization Triggered By Entry Into Mitosis Cytoplasmic In Interphase Cytoplasmic In Metaphase Cells From Prophase To Metaphase Accumulates At The Developing Spindle Poles And Their Associated Microtubules During Anaphase Accumulates At The Spindle Midzone Localization To The Central Spindle And Midbody During Anaphase Is Dependent Upon Prc1 And Cit Presence In Cells Ready To Undergo Abscission Concentrates At The Contractile Ring
Alternative ELISA Names	Kinesin-Like Protein Kif14 ELISA kit KIF14 ELISA kit KIAA0042 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human KIF14 (Kinesin Family, Member 14) Sandwich ELISA Kit Ready-To-Use (STJE0016537)