Anti-CCNT2 antibody (510-590 aa) (STJ191670) STJ191670 上海玉博生物科技有限公司

Anti-CCNT2 antibody (510-590 aa) (STJ191670)

简单介绍

Anti-CCNT2 antibody (510-590 aa) (STJ191670)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cyclin-T2 (510-590 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCNT2
Gene ID:	905
Uniprot ID:	CCNT2_HUMAN
Immunogen Region:	510-590 aa
Specificity:	CCNT2 Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 510-590

Function	Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II). The activity of this complex is regulated by binding with 7SK snRNA. Plays a role during muscle differentiation.P-TEFB complex interacts with MYOD1.this tripartite complex promotes the transcriptional activity of MYOD1 through its CDK9-mediated phosphorylation and binds the chromatin of promoters and enhancers of muscle-specific genes.this event correlates with hyperphosphorylation of the CTD domain of RNA pol II. In addition, enhances MYOD1-dependent transcription through interaction with PKN1. Involved in early embryo development. (Microbial infection) Promotes transcriptional activation of early and late herpes simplex virus 1/HHV-1 promoters.
Protein Name	Cyclin-T2 Cyct2
Database Links	Reactome: R-HSA-112382 Reactome: R-HSA-167152 Reactome: R-HSA-167287 Reactome: R-HSA-167290 Reactome: R-HSA-2173796 Reactome: R-HSA-674695 Reactome: R-HSA-6796648 Reactome: R-HSA-6807505 Reactome: R-HSA-75955
Cellular Localisation	Cytoplasm Perinuclear Region Nucleus Nucleus In Differentiating Cells
Alternative Antibody Names	Anti-Cyclin-T2 antibody Anti-Cyct2 antibody Anti-CCNT2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录