Anti-BAG5 antibody (N-Term) (STJ70196) STJ70196-100 上海玉博生物科技有限公司

Anti-BAG5 antibody (N-Term) (STJ70196)

简单介绍

Anti-BAG5 antibody (N-Term) (STJ70196)

产品描述

Host:	Goat
Applications:	Pep-ELISA/WB/IHC
Reactivity:	Human/Mouse/Rat/Dog/Cow
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-BAG5 (N-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-1-3µg/ml IHC-3.75µg/ml ELISA-antibody detection limit dilution 1:64000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	BAG5
Gene ID:	9529
Uniprot ID:	BAG5_HUMAN
Immunogen Region:	N-Term
Accession Number:	NP_001015049.1; NP_004864.1; NP_001015048.1
Specificity:	Variants (NP_004864.1; NP_001015048.1) encode the same isoform.
Immunogen Sequence:	DMGNQHPSISRLQ

Function	Co-chaperone for HSP/HSP70 proteins. It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding. Has an essential role in maintaining proteostasis at junctional membrane complexes (JMC), where it may function as a scaffold between the HSPA8 chaperone and JMC proteins enabling correct, HSPA8-dependent JMC protein folding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN.
Protein Name	Bag Family Molecular Chaperone Regulator 5 Bag-5 Bcl-2-Associated Athanogene 5
Database Links	Reactome: R-HSA-3371453
Cellular Localisation	In Cardiomyocytes Localized At Specialized Membrane Contact Sites Between T-Tubules And The Sarcoplasmic Reticulum Known As Junctional Membrane Complexes
Alternative Antibody Names	Anti-Bag Family Molecular Chaperone Regulator 5 antibody Anti-Bag-5 antibody Anti-Bcl-2-Associated Athanogene 5 antibody Anti-BAG5 antibody Anti-KIAA0873 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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