Human KLK14 (Kallikrein 14) Sandwich ELISA Kit (STJE0010189) STJE0010189 上海玉博生物科技有限公司

Human KLK14 (Kallikrein 14) Sandwich ELISA Kit (STJE0010189)

简单介绍

Human KLK14 (Kallikrein 14) Sandwich ELISA Kit (STJE0010189)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.044ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This KLK14 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	KLK14
Gene ID:	43847
Uniprot ID:	KLK14_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Highly expressed in CNS, bone marrow and fetal liver. Also expressed in breast, thyroid, kidney, colon, pancreas, spleen, prostate, uterus, small intestine, placenta and skeletal muscle. Among 40 tissues tested, the highest expression is detected in skin followed by breast and prostate (at protein level). Expressed in stratum corneum by sweat ducts and sweat glands and detected in sweat (at protein level).
Post Translational Modifications	Proteolytic cleavage of the activation peptide produces the active enzyme.
Function	Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis.
Protein Name	Kallikrein-14 Hk14 Kallikrein-Like Protein 6 Klk-L6
Database Links	Reactome: R-HSA-6809371
Cellular Localisation	Secreted Extracellular Space
Alternative ELISA Names	Kallikrein-14 ELISA kit Hk14 ELISA kit Kallikrein-Like Protein 6 ELISA kit Klk-L6 ELISA kit KLK14 ELISA kit KLKL6 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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