Human KRT14 (Keratin 14) Sandwich ELISA Kit Ready-To-Use (STJE0016606) STJE0016606 上海玉博生物科技有限公司

Human KRT14 (Keratin 14) Sandwich ELISA Kit Ready-To-Use (STJE0016606)

简单介绍

Human KRT14 (Keratin 14) Sandwich ELISA Kit Ready-To-Use (STJE0016606)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.053ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This KRT14 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	KRT14
Gene ID:	3861
Uniprot ID:	K1C14_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Expressed in the corneal epithelium (at protein level). Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.
Post Translational Modifications	A disulfide bond is formed between rather than within filaments and promotes the formation of a keratin filament cage around the nucleus. Ubiquitinated by the BCR(KLHL24) E3 ubiquitin ligase complex.
Function	The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Protein Name	Keratin - Type I Cytoskeletal 14 Cytokeratin-14 Ck-14 Keratin-14 K14
Database Links	Reactome: R-HSA-446107 Reactome: R-HSA-6805567 Reactome: R-HSA-6809371
Cellular Localisation	Cytoplasm Nucleus Expressed In Both As A Filamentous Pattern
Alternative ELISA Names	Keratin - Type I Cytoskeletal 14 ELISA kit Cytokeratin-14 ELISA kit Ck-14 ELISA kit Keratin-14 ELISA kit K14 ELISA kit KRT14 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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