Human KRT5 (Keratin 5) Sandwich ELISA Kit Ready-To-Use (STJE0016620) STJE0016620 上海玉博生物科技有限公司

Human KRT5 (Keratin 5) Sandwich ELISA Kit Ready-To-Use (STJE0016620)

简单介绍

Human KRT5 (Keratin 5) Sandwich ELISA Kit Ready-To-Use (STJE0016620)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	6.2pg/mL
Detection Limit:	15.6-1000pg/mL
Short Description:	This KRT5 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	KRT5
Gene ID:	3852
Uniprot ID:	K2C5_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity	Expressed in corneal epithelium (at protein level). Expressed in keratinocytes (at protein level).
Post Translational Modifications	Phosphorylated by CDK1, AURKB and Rho-kinase, phosphorylation is regulated by the cell cycle. Thr-24 phosphorylation, mediated by CDK1, peaks during prometaphase or metaphase cells with phosphorylated filamentous structures evident throughout the cytoplasm during early mitosis. CDK1 phosphorylates Thr-24 in mitotic cells at the site of injury. O-glycosylated.
Function	Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress. Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes.
Protein Name	Keratin - Type Ii Cytoskeletal 5 58 Kda Cytokeratin Cytokeratin-5 Ck-5 Keratin-5 K5 Type-Ii Keratin Kb5
Database Links	Reactome: R-HSA-446107 Reactome: R-HSA-6805567 Reactome: R-HSA-6809371
Cellular Localisation	Cytoplasm
Alternative ELISA Names	Keratin - Type Ii Cytoskeletal 5 ELISA kit 58 Kda Cytokeratin ELISA kit Cytokeratin-5 ELISA kit Ck-5 ELISA kit Keratin-5 ELISA kit K5 ELISA kit Type-Ii Keratin Kb5 ELISA kit KRT5 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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