Anti-CD123/IL3RA antibody [6H6] {PE} (STJA0000705) STJA0000705 上海玉博生物科技有限公司

Anti-CD123/IL3RA antibody [6H6] {PE} (STJA0000705)

简单介绍

Anti-CD123/IL3RA antibody [6H6] {PE} (STJA0000705)

产品描述

Host:	Mouse
Applications:	FC
Reactivity:	Human
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-Interleukin-3 receptor subunit alpha is suitable for use in Flow Cytometry research applications.

Clonality:	Monoclonal
Clone ID:	6H6
Conjugation:	PE
Isotype:	IgG1k
Formulation:	PBS with 0.05% Proclin300, 1% BSA
Storage Instruction:	Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.

Post Translational Modifications	Ubiquitinated by RNFT2 in response to IL3. Ubiquitination leads ligand-induced degradation by the proteasome.
Function	Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program.
Protein Name	Interleukin-3 Receptor Subunit Alpha Il-3 Receptor Subunit Alpha Il-3r Subunit Alpha Il-3r-Alpha Il-3ra Cd Antigen Cd123
Database Links	Reactome: R-HSA-512988 Reactome: R-HSA-5673001 Reactome: R-HSA-912526
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Interleukin-3 Receptor Subunit Alpha antibody Anti-Il-3 Receptor Subunit Alpha antibody Anti-Il-3r Subunit Alpha antibody Anti-Il-3r-Alpha antibody Anti-Il-3ra antibody Anti-Cd Antigen Cd123 antibody Anti-IL3RA antibody Anti-IL3R antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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