Anti-BCAR1 antibody (Internal) (STJ73016) STJ73016-100 上海玉博生物科技有限公司

Anti-BCAR1 antibody (Internal) (STJ73016)

如果您对该产品感兴趣的话，可以
产品名称：Anti-BCAR1 antibody (Internal) (STJ73016)
产品型号：STJ73016-100
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-BCAR1 antibody (Internal) (STJ73016)

产品描述

Host:	Goat
Applications:	Pep-ELISA/WB/IHC
Reactivity:	Human/Mouse/Rat/Dog
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-BCAR1 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-1-3µg/ml IHC-Recommended concentration, 5-10µg/ml ELISA-antibody detection limit dilution 1:128000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	BCAR1
Gene ID:	9564
Uniprot ID:	BCAR1_HUMAN
Immunogen Region:	Internal
Accession Number:	NP_001164185.1; NP_001164186.1; NP_001164187.1; NP_001164188.1; NP_001164189.1; NP_055382.2; NP_001164190.1; NP_001164191.1; NP_001164192.1
Specificity:	This antibody is expected to recognize reported isoforms1, 2, 3, 5, 6 and 7.
Immunogen Sequence:	KQTSTFSKQTPHH

Post Translational Modifications	PTK2/FAK1 activation mediates phosphorylation at the YDYVHL motif.phosphorylation is most likely catalyzed by SRC family members. SRC-family kinases are recruited to the phosphorylated sites and can phosphorylate other tyrosine residues. Tyrosine phosphorylation is triggered by integrin-mediated adhesion of cells to the extracellular matrix. Dephosphorylated by PTPN14 at Tyr-128. Phosphorylated by SRC kinase in a EDN1- and PTK2B-mediated manner.phosphorylation strengthens its interaction with BCAR3 as part of the PTK2B/BCAR1/BCAR3/RAP1 signaling pathway.
Function	Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration and cell branching. Involved in the BCAR3-mediated inhibition of TGFB signaling.
Protein Name	Breast Cancer Anti-Estrogen Resistance Protein 1 Crk-Associated Substrate Cas Scaffolding Protein Family Member 1 P130cas
Database Links	Reactome: R-HSA-186763 Reactome: R-HSA-372708 Reactome: R-HSA-4420097 Reactome: R-HSA-8849471
Cellular Localisation	Cell Junction Focal Adhesion Cytoplasm Cell Projection Axon Unphosphorylated Form Localizes In The Cytoplasm Localizes To Focal Adhesion Sites Following Integrin Engagement
Alternative Antibody Names	Anti-Breast Cancer Anti-Estrogen Resistance Protein 1 antibody Anti-Crk-Associated Substrate antibody Anti-Cas Scaffolding Protein Family Member 1 antibody Anti-P130cas antibody Anti-BCAR1 antibody Anti-CAS antibody Anti-CASS1 antibody Anti-CRKAS antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Anti-BCAR1 antibody (Internal) (STJ73016)