Human LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1) Sandwich ELISA Kit (STJE0010297) STJE0010297 上海玉博生物科技有限公司

Human LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1) Sandwich ELISA Kit (STJE0010297)

如果您对该产品感兴趣的话，可以
产品名称：Human LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1) Sandwich ELISA Kit (STJE0010297)
产品型号：STJE0010297
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1) Sandwich ELISA Kit (STJE0010297)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.056ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This LDLRAP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	LDLRAP1
Gene ID:	26119
Uniprot ID:	ARH_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Expressed at high levels in the kidney, liver, and placenta, with lower levels detectable in brain, heart, muscle, colon, spleen, intestine, lung, and leukocytes.
Post Translational Modifications
Function	Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytosis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface. Required for trafficking of LRP2 to the endocytic recycling compartment which is necessary for LRP2 proteolysis, releasing a tail fragment which translocates to the nucleus and mediates transcriptional repression.
Protein Name	Low Density Lipoprotein Receptor Adapter Protein 1 Autosomal Recessive Hypercholesterolemia Protein
Database Links	Reactome: R-HSA-196791 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-8964026 Reactome: R-HSA-8964038 Reactome: R-HSA-9758890
Cellular Localisation	Cytoplasm
Alternative ELISA Names	Low Density Lipoprotein Receptor Adapter Protein 1 ELISA kit Autosomal Recessive Hypercholesterolemia Protein ELISA kit LDLRAP1 ELISA kit ARH ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Human LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1) Sandwich ELISA Kit (STJE0010297)