Human LFA1a (Lymphocyte Function Associated Antigen 1 Alpha) Sandwich ELISA Kit Ready-To-Use (STJE0016710) STJE0016710 上海玉博生物科技有限公司

Human LFA1a (Lymphocyte Function Associated Antigen 1 Alpha) Sandwich ELISA Kit Ready-To-Use (STJE0016710)

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产品名称：Human LFA1a (Lymphocyte Function Associated Antigen 1 Alpha) Sandwich ELISA Kit Ready-To-Use (STJE0016710)
产品型号：STJE0016710
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human LFA1a (Lymphocyte Function Associated Antigen 1 Alpha) Sandwich ELISA Kit Ready-To-Use (STJE0016710)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.055ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This LFA1a Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	ITGAL
Gene ID:	3683
Uniprot ID:	ITAL_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Leukocytes.
Post Translational Modifications	In resting T-cells, up to 40% of surface ITGAL is constitutively phosphorylated. Phosphorylation causes conformational changes needed for ligand binding and is necessary for activation by some physiological agents.
Function	Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R. Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15.the interaction is mediated by ITGAL. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Required for generation of common lymphoid progenitor cells in bone marrow, indicating a role in lymphopoiesis. Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages.
Protein Name	Integrin Alpha-L Cd11 Antigen-Like Family Member A Leukocyte Adhesion Glycoprotein Lfa-1 Alpha Chain Lfa-1a Leukocyte Function-Associated Molecule 1 Alpha Chain Cd Antigen Cd11a
Database Links	Reactome: R-HSA-198933 Reactome: R-HSA-202733 Reactome: R-HSA-216083 Reactome: R-HSA-6798695 Reactome: R-HSA-8949275
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative ELISA Names	Integrin Alpha-L ELISA kit Cd11 Antigen-Like Family Member A ELISA kit Leukocyte Adhesion Glycoprotein Lfa-1 Alpha Chain ELISA kit Lfa-1a ELISA kit Leukocyte Function-Associated Molecule 1 Alpha Chain ELISA kit Cd Antigen Cd11a ELISA kit ITGAL ELISA kit CD11A ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human LFA1a (Lymphocyte Function Associated Antigen 1 Alpha) Sandwich ELISA Kit Ready-To-Use (STJE0016710)