Anti-CD14 antibody (1-100 aa) [ABT021] (STJ197096) STJ197096 上海玉博生物科技有限公司

Anti-CD14 antibody (1-100 aa) [ABT021] (STJ197096)

如果您对该产品感兴趣的话，可以
产品名称：Anti-CD14 antibody (1-100 aa) [ABT021] (STJ197096)
产品型号：STJ197096
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CD14 antibody (1-100 aa) [ABT021] (STJ197096)

产品描述

Host:	Mouse
Applications:	IHC/WB/IF
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-Monocyte differentiation antigen CD14 (1-100 aa) is suitable for use in Immunohistochemistry, Western Blot and Immunofluorescence research applications.

Clonality:	Monoclonal
Clone ID:	ABT021
Conjugation:	Unconjugated
Isotype:	IgG2bk
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range:	IHC-P 1:100-500 WB 1:200-1000 IF 1:100-500
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CD14
Gene ID:	929
Uniprot ID:	CD14_HUMAN
Immunogen Region:	1-100 aa
Specificity:	The antibody can specifically recognize human CD14 protein.
Immunogen:	Synthesized peptide derived from the human CD14 at the amino acid range 1-100

Post Translational Modifications	N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
Function	Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).
Protein Name	Monocyte Differentiation Antigen Cd14 Myeloid Cell-Specific Leucine-Rich Glycoprotein Cd Antigen Cd14 Cleaved Into - Monocyte Differentiation Antigen Cd14 - Urinary Form - Monocyte Differentiation Antigen Cd14 - Membrane-Bound Form
Database Links	Reactome: R-HSA-1236974 Reactome: R-HSA-140534 Reactome: R-HSA-166016 Reactome: R-HSA-166020 Reactome: R-HSA-166058 Reactome: R-HSA-166166 Reactome: R-HSA-168179 Reactome: R-HSA-168188 Reactome: R-HSA-2562578 Reactome: R-HSA-5602498 Reactome: R-HSA-5603041 Reactome: R-HSA-5686938 Reactome: R-HSA-6798695 Reactome: R-HSA-936964 Reactome: R-HSA-937041 Reactome: R-HSA-937072 Reactome: R-HSA-975163
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Secreted Membrane Raft Golgi Apparatus Secreted Forms May Arise By Cleavage Of The Gpi Anchor
Alternative Antibody Names	Anti-Monocyte Differentiation Antigen Cd14 antibody Anti-Myeloid Cell-Specific Leucine-Rich Glycoprotein antibody Anti-Cd Antigen Cd14 Cleaved Into - Monocyte Differentiation Antigen Cd14 - Urinary Form - Monocyte Differentiation Antigen Cd14 - Membrane-Bound Form antibody Anti-CD14 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Anti-CD14 antibody (1-100 aa) [ABT021] (STJ197096)