Anti-BCL11B antibody (570-650 aa) (STJ191804) STJ191804 上海玉博生物科技有限公司

Anti-BCL11B antibody (570-650 aa) (STJ191804)

简单介绍

Anti-BCL11B antibody (570-650 aa) (STJ191804)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-B-cell lymphoma/leukemia 11B (570-650 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BCL11B
Gene ID:	64919
Uniprot ID:	BC11B_HUMAN
Immunogen Region:	570-650 aa
Specificity:	BC11B Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 570-650

Post Translational Modifications	Sumoylated with SUMO1.
Function	Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus. Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes. Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC-rich response element. May also function in the P53-signaling pathway.
Protein Name	B-Cell Lymphoma/Leukemia 11b Bcl-11b B-Cell Cll/Lymphoma 11b Coup-Tf-Interacting Protein 2 Radiation-Induced Tumor Suppressor Gene 1 Protein Hrit1
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-B-Cell Lymphoma/Leukemia 11b antibody Anti-Bcl-11b antibody Anti-B-Cell Cll/Lymphoma 11b antibody Anti-Coup-Tf-Interacting Protein 2 antibody Anti-Radiation-Induced Tumor Suppressor Gene 1 Protein antibody Anti-Hrit1 antibody Anti-BCL11B antibody Anti-CTIP2 antibody Anti-RIT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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