Human LIPD (Lipase, Lipoprotein) Sandwich ELISA Kit (STJE0010352) STJE0010352 上海玉博生物科技有限公司

Human LIPD (Lipase, Lipoprotein) Sandwich ELISA Kit (STJE0010352)

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产品名称：Human LIPD (Lipase, Lipoprotein) Sandwich ELISA Kit (STJE0010352)
产品型号：STJE0010352
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human LIPD (Lipase, Lipoprotein) Sandwich ELISA Kit (STJE0010352)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	8.65pg/mL
Detection Limit:	23.4-1500pg/mL
Short Description:	This LIPD Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	LPL
Gene ID:	4023
Uniprot ID:	LIPL_HUMAN
Sample Type:	serum, plasma, tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Detected in blood plasma. Detected in milk (at protein level).
Post Translational Modifications	Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
Function	Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
Protein Name	Lipoprotein Lipase Lpl Phospholipase A1
Database Links	Reactome: R-HSA-381340 Reactome: R-HSA-8963889 Reactome: R-HSA-8963901 Reactome: R-HSA-975634
Cellular Localisation	Cell Membrane Peripheral Membrane Protein Extracellular Side Secreted Extracellular Space Extracellular Matrix Newly Synthesized Lpl Binds To Cell Surface Heparan Proteoglycans And Is Then Released By Heparanase Subsequently It Becomes Attached To Heparan Proteoglycan On Endothelial Cells Locates To The Plasma Membrane Of Microvilli Of Hepatocytes With Triglyceride-Rich Lipoproteins (Trl) Some Of The Bound Lpl Is Then Internalized And Located Inside Non-Coated Endocytic Vesicles
Alternative ELISA Names	Lipoprotein Lipase ELISA kit Lpl ELISA kit Phospholipase A1 ELISA kit LPL ELISA kit LIPD ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human LIPD (Lipase, Lipoprotein) Sandwich ELISA Kit (STJE0010352)