Human LNPEP (Leucyl/Cystinyl Aminopeptidase) Sandwich ELISA Kit (STJE0010374) STJE0010374 上海玉博生物科技有限公司

Human LNPEP (Leucyl/Cystinyl Aminopeptidase) Sandwich ELISA Kit (STJE0010374)

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产品名称：Human LNPEP (Leucyl/Cystinyl Aminopeptidase) Sandwich ELISA Kit (STJE0010374)
产品型号：STJE0010374
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human LNPEP (Leucyl/Cystinyl Aminopeptidase) Sandwich ELISA Kit (STJE0010374)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.58ng/mL
Detection Limit:	1.56-100ng/mL
Short Description:	This LNPEP Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	LNPEP
Gene ID:	4012
Uniprot ID:	LCAP_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Highly expressed in placenta, heart, kidney and small intestine. Detected at lower levels in neuronal cells in the brain, in skeletal muscle, spleen, liver, testes and colon.
Post Translational Modifications	The pregnancy serum form is derived from the membrane-bound form by proteolytic processing. N-glycosylated.
Function	Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain.
Protein Name	Leucyl-Cystinyl Aminopeptidase Cystinyl Aminopeptidase Insulin-Regulated Membrane Aminopeptidase Insulin-Responsive Aminopeptidase Irap Oxytocinase Otase Placental Leucine Aminopeptidase P-Lap Cleaved Into - Leucyl-Cystinyl Aminopeptidase - Pregnancy Serum Form
Database Links	Reactome: R-HSA-1236977 Reactome: R-HSA-1445148 Reactome: R-HSA-983168
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein In Brain Only The Membrane-Bound Form Is Found The Protein Resides In Intracellular Vesicles Together With Glut4 And Can Then Translocate To The Cell Surface In Response To Insulin And/Or Oxytocin Localization May Be Determined By Dileucine Internalization Motifs And/Or By Interaction With Tankyrases Leucyl-Cystinyl Aminopeptidase Pregnancy Serum Form: Secreted During Pregnancy Serum Levels Are Low In The First Trimester Rise Progressively During The Second And Third Trimester And Decrease Rapidly After Parturition
Alternative ELISA Names	Leucyl-Cystinyl Aminopeptidase ELISA kit Cystinyl Aminopeptidase ELISA kit Insulin-Regulated Membrane Aminopeptidase ELISA kit Insulin-Responsive Aminopeptidase ELISA kit Irap ELISA kit Oxytocinase ELISA kit Otase ELISA kit Placental Leucine Aminopeptidase ELISA kit P-Lap Cleaved Into - Leucyl-Cystinyl Aminopeptidase - Pregnancy Serum Form ELISA kit LNPEP ELISA kit OTASE ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human LNPEP (Leucyl/Cystinyl Aminopeptidase) Sandwich ELISA Kit (STJE0010374)