Anti-BCL2L2 antibody (1-193) (STJ115432) STJ115432 上海玉博生物科技有限公司

Anti-BCL2L2 antibody (1-193) (STJ115432)

简单介绍

Anti-BCL2L2 antibody (1-193) (STJ115432)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Bcl-W (1-193) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BCL2L2
Gene ID:	599
Uniprot ID:	B2CL2_HUMAN
Immunogen Region:	1-193
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human Bcl-W (NP_001186768.1).
Immunogen Sequence:	MATPASAPDTRALVADFVGY KLRQKGYVCGAGPGEGPAAD PLHQAMRAAGDEFETRFRRT FSDLAAQLHVTPGSAQQRFT QVSDELFQGGPNWGRLVAFF VFGAALCAESVNKEMEPLVG QVQEWMVAYLETRLADWIHS SGGWAEFTALYGDGALEEAR RLREGNWASVRTVLTGAVAL GALVTVGAFFASK

Tissue Specificity	Expressed (at protein level) in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands. Moderate levels found in thymus, ovary and small intestine. Not detected in salivary gland, muscle or liver. Also expressed in cell lines of myeloid, fibroblast and epithelial origin. Not detected in most lymphoid cell lines.
Function	Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
Protein Name	Bcl-2-Like Protein 2 Bcl2-L-2 Apoptosis Regulator Bcl-W
Cellular Localisation	Mitochondrion Membrane Peripheral Membrane Protein Loosely Associated With The Mitochondrial Membrane In Healthy Cells During Apoptosis Tightly Bound To The Membrane
Alternative Antibody Names	Anti-Bcl-2-Like Protein 2 antibody Anti-Bcl2-L-2 antibody Anti-Apoptosis Regulator Bcl-W antibody Anti-BCL2L2 antibody Anti-BCLW antibody Anti-KIAA0271 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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