Human LRP4 (Low Density Lipoprotein Receptor Related Protein 4) Sandwich ELISA Kit Ready-To-Use (STJE0016807) STJE0016807 上海玉博生物科技有限公司

Human LRP4 (Low Density Lipoprotein Receptor Related Protein 4) Sandwich ELISA Kit Ready-To-Use (STJE0016807)

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产品名称：Human LRP4 (Low Density Lipoprotein Receptor Related Protein 4) Sandwich ELISA Kit Ready-To-Use (STJE0016807)
产品型号：STJE0016807
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human LRP4 (Low Density Lipoprotein Receptor Related Protein 4) Sandwich ELISA Kit Ready-To-Use (STJE0016807)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.103ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This LRP4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	LRP4
Gene ID:	4038
Uniprot ID:	LRP4_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Expressed in bone.present in osteoblasts and osteocytes. No expression is observed in osteoclast. Expressed in several regions of the brain.
Post Translational Modifications
Function	Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Alternatively, may be involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. More generally, has been proposed to function as a cell surface endocytic receptor binding and internalizing extracellular ligands for degradation by lysosomes. May play an essential role in the process of digit differentiation.
Protein Name	Low-Density Lipoprotein Receptor-Related Protein 4 Lrp-4 Multiple Epidermal Growth Factor-Like Domains 7
Database Links	Reactome: R-HSA-3000178
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative ELISA Names	Low-Density Lipoprotein Receptor-Related Protein 4 ELISA kit Lrp-4 ELISA kit Multiple Epidermal Growth Factor-Like Domains 7 ELISA kit LRP4 ELISA kit KIAA0816 ELISA kit LRP10 ELISA kit MEGF7 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human LRP4 (Low Density Lipoprotein Receptor Related Protein 4) Sandwich ELISA Kit Ready-To-Use (STJE0016807)