Anti-BERP/RNF22 antibody (N-Term) (STJ70324) STJ70324-100 上海玉博生物科技有限公司

Anti-BERP/RNF22 antibody (N-Term) (STJ70324)

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产品名称：Anti-BERP/RNF22 antibody (N-Term) (STJ70324)
产品型号：STJ70324-100
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-BERP/RNF22 antibody (N-Term) (STJ70324)

产品描述

Host:	Goat
Applications:	Pep-ELISA/WB
Reactivity:	Human/Mouse/Rat/Dog/Cow
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-BERP/RNF22 (N-Term) is suitable for use in ELISA and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	ELISA-antibody detection limit dilution 1:64000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	TRIM3
Gene ID:	10612
Uniprot ID:	TRIM3_HUMAN
Immunogen Region:	N-Term
Accession Number:	NP_006449.2; NP_150594.2
Specificity:	Both variants (NP_006449.2; NP_150594.2;) represent the same protein. This antibody is expected to recognise all three human isoforms of this protein.
Immunogen Sequence:	AKREDSPGPEVQP

Function	E3 ubiquitin ligase that plays essential roles in neuronal functions such as regulation of neuronal plasticity, learning, and memory. In addition to its neuronal functions, participates in other biological processes such as innate immunity or cell cycle regulation. Component of the cytoskeleton-associated recycling or transport complex in neurons, polyubiquitinates gamma-actin, thus regulating neuronal plasticity, learning, and memory. Ubiquitinates postsynaptic scaffold GKAP, a neuronal substrate involved in synaptic remodeling and thereby modulates dendritic spine morphology. Positively regulates motility of microtubule-dependent motor protein KIF21B. Induces growth arrest via its RING-dependent E3 ligase activity and ubiquinates CDKN1A. Positively regulates TLR3-mediated signaling by mediating 'Lys-63'-linked polyubiquitination of TLR3. In turn, promotes the recognition and sorting of polyubiquitinated TLR3 by the ESCRT complexes.
Protein Name	Tripartite Motif-Containing Protein 3 Brain-Expressed Ring Finger Protein Ring Finger Protein 22 Ring Finger Protein 97
Database Links	Reactome: R-HSA-877300
Cellular Localisation	Cytoplasm Early Endosome Golgi Apparatus Trans-Golgi Network Cell Projection Dendrite Mainly Located In The Golgi Apparatus And Transported To The Early Endosomes Upon Stimulation With Dsrna
Alternative Antibody Names	Anti-Tripartite Motif-Containing Protein 3 antibody Anti-Brain-Expressed Ring Finger Protein antibody Anti-Ring Finger Protein 22 antibody Anti-Ring Finger Protein 97 antibody Anti-TRIM3 antibody Anti-BERP antibody Anti-RNF22 antibody Anti-RNF97 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-BERP/RNF22 antibody (N-Term) (STJ70324)