Human MEP1b (Meprin A Beta) Sandwich ELISA Kit Ready-To-Use (STJE0016944) STJE0016944 上海玉博生物科技有限公司

Human MEP1b (Meprin A Beta) Sandwich ELISA Kit Ready-To-Use (STJE0016944)

如果您对该产品感兴趣的话，可以
产品名称：Human MEP1b (Meprin A Beta) Sandwich ELISA Kit Ready-To-Use (STJE0016944)
产品型号：STJE0016944
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human MEP1b (Meprin A Beta) Sandwich ELISA Kit Ready-To-Use (STJE0016944)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.117ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This MEP1b Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	MEP1B
Gene ID:	4225
Uniprot ID:	MEP1B_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	The major site of expression is the brush border membrane of small intestinal and kidney epithelial cells.
Post Translational Modifications	N-glycosylated.contains high mannose and/or complex biantennary structures. O-glycosylation protect the C-terminal region from proteolytic cleavage and diminish secretion, this seems to be specific to human. Proteolytically activated by trypsin in the intestinal lumen and kallikrein-related peptidases in other tissues.
Function	Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.
Protein Name	Meprin A Subunit Beta Endopeptidase-2 Meprin B N-Benzoyl-L-Tyrosyl-P-Amino-Benzoic Acid Hydrolase Subunit Beta Paba Peptide Hydrolase Pph Beta
Database Links
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Secreted Homodimers Are Essentially Membrane Bound But May Also Be Shed From The Surface By Adam-10 And Adam-17
Alternative ELISA Names	Meprin A Subunit Beta ELISA kit Endopeptidase-2 ELISA kit Meprin B ELISA kit N-Benzoyl-L-Tyrosyl-P-Amino-Benzoic Acid Hydrolase Subunit Beta ELISA kit Paba Peptide Hydrolase ELISA kit Pph Beta ELISA kit MEP1B ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Human MEP1b (Meprin A Beta) Sandwich ELISA Kit Ready-To-Use (STJE0016944)