Human METAP2 (Methionyl Aminopeptidase 2) Sandwich ELISA Kit Ready-To-Use (STJE0016949) STJE0016949 上海玉博生物科技有限公司

Human METAP2 (Methionyl Aminopeptidase 2) Sandwich ELISA Kit Ready-To-Use (STJE0016949)

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产品名称：Human METAP2 (Methionyl Aminopeptidase 2) Sandwich ELISA Kit Ready-To-Use (STJE0016949)
产品型号：STJE0016949
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human METAP2 (Methionyl Aminopeptidase 2) Sandwich ELISA Kit Ready-To-Use (STJE0016949)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.058ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This METAP2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	METAP2
Gene ID:	10988
Uniprot ID:	MAP2_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
Function	Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.
Protein Name	Methionine Aminopeptidase 2 Map 2 Metap 2 Initiation Factor 2-Associated 67 Kda Glycoprotein P67 P67eif2 Peptidase M
Database Links	Reactome: R-HSA-2514859
Cellular Localisation	Cytoplasm About 30% Of Expressed Metap2 Associates With Polysomes
Alternative ELISA Names	Methionine Aminopeptidase 2 ELISA kit Map 2 ELISA kit Metap 2 ELISA kit Initiation Factor 2-Associated 67 Kda Glycoprotein ELISA kit P67 ELISA kit P67eif2 ELISA kit Peptidase M ELISA kit METAP2 ELISA kit MNPEP ELISA kit P67EIF2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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