Anti-BFSP1 antibody (281-540) (STJ22793) STJ22793 上海玉博生物科技有限公司

Anti-BFSP1 antibody (281-540) (STJ22793)

简单介绍

Anti-BFSP1 antibody (281-540) (STJ22793)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-BFSP1 (281-540) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BFSP1
Gene ID:	631
Uniprot ID:	BFSP1_HUMAN
Immunogen Region:	281-540
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 281-540 of human BFSP1 (NP_001155177.1).
Immunogen Sequence:	EESESKFESESKEVSPLTQE GAPEDVPDGGQISKGFGKLY RKVKEKVRSPKEPETPTELY TKERHVLVTGDANYVDPRFY VSSITAKGGVAVSVAEDSVL YDGQVEPSPESPKPPLENGQ VGLQEKEDGQPIDQQPIDKE IEPDGAELEGPEEKREGEER DEESRRPCAMVTPGAEEPSI PEPPKPAADQDGAEVLGTRS RSLPEKGPPKALAYKTVEVV ESIEKISTESIQTYEETAV

Tissue Specificity	Expressed in the cortex and nucleus of the retina lens (at protein level).
Post Translational Modifications	Proteolytically cleaved during lens cell fiber differentiation with increased fragmentation as fiber cell age increases. Filensin C-terminal fragment: Myristoylated at Gly-434 following proteolytic cleavage at Asp-433. Filensin N-terminal fragment: Acetylated at Ala-42 following proteolytic cleavage at Leu-41.
Function	Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. Involved in altering the calcium regulation of MIP water permeability.
Protein Name	Filensin Beaded Filament Structural Protein 1 Lens Fiber Cell Beaded-Filament Structural Protein Cp 115 Cp115 Lens Intermediate Filament-Like Heavy Lifl-H Cleaved Into - Filensin C-Terminal Fragment - Filensin N-Terminal Fragment
Cellular Localisation	Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytoskeleton Cell Cortex
Alternative Antibody Names	Anti-Filensin antibody Anti-Beaded Filament Structural Protein 1 antibody Anti-Lens Fiber Cell Beaded-Filament Structural Protein Cp 115 antibody Anti-Cp115 antibody Anti-Lens Intermediate Filament-Like Heavy antibody Anti-Lifl-H Cleaved Into - Filensin C-Terminal Fragment - Filensin N-Terminal Fragment antibody Anti-BFSP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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