Anti-Bin3 antibody (Internal) (STJ71405) STJ71405-100 上海玉博生物科技有限公司

Anti-Bin3 antibody (Internal) (STJ71405)

简单介绍

Anti-Bin3 antibody (Internal) (STJ71405)

产品描述

Host:	Goat
Applications:	Pep-ELISA/WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-Bin3 (Internal) is suitable for use in ELISA and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-0.3-1µg/ml ELISA-antibody detection limit dilution 1:16000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Function	S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA (7SK RNA), leading to stabilize it. Also has a non-enzymatic function as part of the 7SK RNP complex: the 7SK RNP complex sequesters the positive transcription elongation factor b (P-TEFb) in a large inactive 7SK RNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. The 7SK RNP complex also promotes snRNA gene transcription by RNA polymerase II via interaction with the little elongation complex (LEC). In the 7SK RNP complex, MEPCE is required to stabilize 7SK RNA and facilitate the assembly of 7SK RNP complex. MEPCE has a non-enzymatic function in the 7SK RNP complex.interaction with LARP7 within the 7SK RNP complex occluding its catalytic center.
Protein Name	7sk Snrna Methylphosphate Capping Enzyme Mepce Bicoid-Interacting Protein 3 Homolog Bin3 Homolog
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-7sk Snrna Methylphosphate Capping Enzyme antibody Anti-Mepce antibody Anti-Bicoid-Interacting Protein 3 Homolog antibody Anti-Bin3 Homolog antibody Anti-MEPCE antibody Anti-BCDIN3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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