Human MR (Mineralocorticoid Receptor) Sandwich ELISA Kit Ready-To-Use (STJE0017110) STJE0017110 上海玉博生物科技有限公司

Human MR (Mineralocorticoid Receptor) Sandwich ELISA Kit Ready-To-Use (STJE0017110)

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产品名称：Human MR (Mineralocorticoid Receptor) Sandwich ELISA Kit Ready-To-Use (STJE0017110)
产品型号：STJE0017110
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human MR (Mineralocorticoid Receptor) Sandwich ELISA Kit Ready-To-Use (STJE0017110)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.112ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This MR Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	NR3C2
Gene ID:	4306
Uniprot ID:	MCR_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Ubiquitous. Highly expressed in distal tubules, convoluted tubules and cortical collecting duct in kidney, and in sweat glands. Detected at lower levels in cardiomyocytes, in epidermis and in colon enterocytes.
Post Translational Modifications	Phosphorylated.
Function	Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Protein Name	Mineralocorticoid Receptor Mr Nuclear Receptor Subfamily 3 Group C Member 2
Database Links	Reactome: R-HSA-3371497 Reactome: R-HSA-383280 Reactome: R-HSA-4090294
Cellular Localisation	Cytoplasm Nucleus Endoplasmic Reticulum Membrane Peripheral Membrane Protein Cytoplasmic And Nuclear In The Absence Of Ligand Nuclear After Ligand-Binding When Bound To Hsd11b2 It Is Found Associated With The Endoplasmic Reticulum Membrane
Alternative ELISA Names	Mineralocorticoid Receptor ELISA kit Mr ELISA kit Nuclear Receptor Subfamily 3 Group C Member 2 ELISA kit NR3C2 ELISA kit MCR ELISA kit MLR ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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