Human MRC2 (C-type mannose receptor 2) CLIA Kit (STJC0000967) STJC0000967 上海玉博生物科技有限公司

Human MRC2 (C-type mannose receptor 2) CLIA Kit (STJC0000967)

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产品名称：Human MRC2 (C-type mannose receptor 2) CLIA Kit (STJC0000967)
产品型号：STJC0000967
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human MRC2 (C-type mannose receptor 2) CLIA Kit (STJC0000967)

产品描述

Applications:	CLIA
Reactivity:	Human
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity:	37.5pg/mL
Detection Limit:	62.5~4000pg/mL
Short Description:	This human MRC2 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.

Storage Instruction:	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time:	3.5h
Detection:	Chemiluminescence

Gene Symbol:	MRC2
Gene ID:	9902
Uniprot ID:	MRC2_HUMAN
Specificity:	This kit recognizes Human MRC2 in samples. No significant cross-reactivity or interference between Human MRC2 and analogues was observed.
Sample Type:	Serum, plasma and other biological fluids

Tissue Specificity	Ubiquitous with low expression in brain, placenta, lung, kidney, pancreas, spleen, thymus and colon. Expressed in endothelial cells, fibroblasts and macrophages. Highly expressed in fetal lung and kidney.
Post Translational Modifications	N-glycosylated.
Function	May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Protein Name	C-Type Mannose Receptor 2 C-Type Lectin Domain Family 13 Member E Endocytic Receptor 180 Macrophage Mannose Receptor 2 Urokinase-Type Plasminogen Activator Receptor-Associated Protein Upar-Associated Protein Urokinase Receptor-Associated Protein Cd Antigen Cd280
Database Links	Reactome: R-HSA-1236978
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative CLIA Names	C-Type Mannose Receptor 2 CLIA kit C-Type Lectin Domain Family 13 Member E CLIA kit Endocytic Receptor 180 CLIA kit Macrophage Mannose Receptor 2 CLIA kit Urokinase-Type Plasminogen Activator Receptor-Associated Protein CLIA kit Upar-Associated Protein CLIA kit Urokinase Receptor-Associated Protein CLIA kit Cd Antigen Cd280 CLIA kit MRC2 CLIA kit CLEC13E CLIA kit ENDO180 CLIA kit KIAA0709 CLIA kit UPARAP CLIA kit
Specificity	This kit recognizes Human MRC2 in samples. No significant cross-reactivity or interference between Human MRC2 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item Specifications Storage

Micro CLIA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent A	1 vial, 5 mL	2-8℃ (Protect from light)
Substrate Reagent B	1 vial, 5 mL	2-8℃ (Protect from light)
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Sample Type Range (%) Average Recovery (%)

Serum(n=8)	93-105	99
EDTA plasma(n=8)	87-100	94
Cell culture media(n=8)	90-104	97

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision

Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (pg/mL)	207.98	480.52	1431.39	212.36	457.99	1359.01
Standard deviation	24.56	44.83	113.37	22.28	40.72	130.33
CV (%)	11.81	9.33	7.92	10.49	8.89	9.59

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human MRC2 (C-type mannose receptor 2) CLIA Kit (STJC0000967)