Anti-BLOC1S2 antibody (44-142) (STJ110314) STJ110314 上海玉博生物科技有限公司

Anti-BLOC1S2 antibody (44-142) (STJ110314)

简单介绍

Anti-BLOC1S2 antibody (44-142) (STJ110314)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-BLOC1S2 (44-142) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BLOC1S2
Gene ID:	282991
Uniprot ID:	BL1S2_HUMAN
Immunogen Region:	44-142
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 44-142 of human BLOC1S2 (NP_776170.2).
Immunogen Sequence:	MFSKMATYLTGELTATSEDY KLLENMNKLTSLKYLEMKDI AINISRNLKDLNQKYAGLQP YLDQINVIEEQVAALEQAAY KLDAYSKKLEAKYKKLEKR

Tissue Specificity	Isoform 1 and isoform 2 are widely expressed. Expressed in various malignant tumor tissues (at protein level).
Function	Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. May play a role in cell proliferation.
Protein Name	Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 2 Bloc-1 Subunit 2 Centrosome-Associated Protein
Cellular Localisation	Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Lysosome Membrane Localizes To The Centrosomes In A Microtubule-Dependent Manner
Alternative Antibody Names	Anti-Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 2 antibody Anti-Bloc-1 Subunit 2 antibody Anti-Centrosome-Associated Protein antibody Anti-BLOC1S2 antibody Anti-BLOS2 antibody Anti-CEAP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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