Human MTR (5-Methyltetrahydrofolate Homocysteine Methyltransferase) Sandwich ELISA Kit (STJE0010771) STJE0010771 上海玉博生物科技有限公司

Human MTR (5-Methyltetrahydrofolate Homocysteine Methyltransferase) Sandwich ELISA Kit (STJE0010771)

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产品名称：Human MTR (5-Methyltetrahydrofolate Homocysteine Methyltransferase) Sandwich ELISA Kit (STJE0010771)
产品型号：STJE0010771
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human MTR (5-Methyltetrahydrofolate Homocysteine Methyltransferase) Sandwich ELISA Kit (STJE0010771)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.115ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This MTR Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	MTR
Gene ID:	4548
Uniprot ID:	METH_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Widely expressed. Expressed at the highest levels in pancreas, heart, brain, skeletal muscle and placenta. Expressed at lower levels in lung, liver and kidney.
Post Translational Modifications
Function	Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
Protein Name	Methionine Synthase Ms 5-Methyltetrahydrofolate--Homocysteine Methyltransferase Cobalamin-Dependent Methionine Synthase Vitamin-B12 Dependent Methionine Synthase
Database Links	Reactome: R-HSA-156581 Reactome: R-HSA-1614635 Reactome: R-HSA-3359467 Reactome: R-HSA-3359469 Reactome: R-HSA-9013407 Reactome: R-HSA-9759218
Cellular Localisation	Cytoplasm
Alternative ELISA Names	Methionine Synthase ELISA kit Ms ELISA kit 5-Methyltetrahydrofolate--Homocysteine Methyltransferase ELISA kit Cobalamin-Dependent Methionine Synthase ELISA kit Vitamin-B12 Dependent Methionine Synthase ELISA kit MTR ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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