Anti-CD2AP antibody (320-400 aa) (STJ191673) STJ191673 上海玉博生物科技有限公司

Anti-CD2AP antibody (320-400 aa) (STJ191673)

简单介绍

Anti-CD2AP antibody (320-400 aa) (STJ191673)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CD2-associated protein (320-400 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CD2AP
Gene ID:	23607
Uniprot ID:	CD2AP_HUMAN
Immunogen Region:	320-400 aa
Specificity:	CD2AP Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 320-400

Post Translational Modifications	Phosphorylated on tyrosine residues.probably by c-Abl, Fyn and c-Src.
Function	Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis. Plays a role in epithelial cell junctions formation.
Protein Name	Cd2-Associated Protein Adapter Protein Cms Cas Ligand With Multiple Sh3 Domains
Database Links	Reactome: R-HSA-373753
Cellular Localisation	Cytoplasm Cytoskeleton Cell Projection Ruffle Cell Junction Colocalizes With F-Actin And Bcar1/P130cas In Membrane Ruffles Located At Podocyte Slit Diaphragm Between Podocyte Foot Processes During Late Anaphase And Telophase Concentrates In The Vicinity Of The Midzone Microtubules And In The Midbody In Late Telophase
Alternative Antibody Names	Anti-Cd2-Associated Protein antibody Anti-Adapter Protein Cms antibody Anti-Cas Ligand With Multiple Sh3 Domains antibody Anti-CD2AP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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