Anti-CD300LF antibody (230-290) (STJ500460) STJ500460-100 上海玉博生物科技有限公司

Anti-CD300LF antibody (230-290) (STJ500460)

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产品名称：Anti-CD300LF antibody (230-290) (STJ500460)
产品型号：STJ500460-100
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CD300LF antibody (230-290) (STJ500460)

产品描述

Host:	Rabbit
Applications:	ELISA/IHC/IP/WB
Reactivity:	Human/Monkey
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CD300LF (230-290) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.5-1.5 µg/µl
Dilution Range:	WB: 1:500 ELISA: 1:10, 000 IP: 1:200 IHC: 1:50-1:150 ICC: 1:50-1:150
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	CD300LF
Gene ID:	146722
Uniprot ID:	CLM1_HUMAN
Immunogen Region:	230-290
Immunogen:	Synthetic peptide taken within amino acid region 230-290 on human CMRF35-like molecule 1/CD300LF.

Tissue Specificity	Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.
Post Translational Modifications	Phosphorylated on tyrosine.
Function	Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition.recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands. May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2. Inhibits osteoclast formation. Induces macrophage cell death upon engagement.
Protein Name	Cmrf35-Like Molecule 1 Clm-1 Cd300 Antigen-Like Family Member F Immune Receptor Expressed On Myeloid Cells 1 Irem-1 Immunoglobulin Superfamily Member 13 Igsf13 Nk Inhibitory Receptor Cd Antigen Cd300f
Database Links	Reactome: R-HSA-198933
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Cmrf35-Like Molecule 1 antibody Anti-Clm-1 antibody Anti-Cd300 Antigen-Like Family Member F antibody Anti-Immune Receptor Expressed On Myeloid Cells 1 antibody Anti-Irem-1 antibody Anti-Immunoglobulin Superfamily Member 13 antibody Anti-Igsf13 antibody Anti-Nk Inhibitory Receptor antibody Anti-Cd Antigen Cd300f antibody Anti-CD300LF antibody Anti-CD300F antibody Anti-CLM1 antibody Anti-IGSF13 antibody Anti-IREM1 antibody Anti-NKIR antibody Anti-UNQ3105 antibody Anti-PRO10111 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CD300LF antibody (230-290) (STJ500460)