Anti-CD303/CLEC4C antibody [201A] {APC} (STJA0001926) STJA0001926 上海玉博生物科技有限公司

Anti-CD303/CLEC4C antibody [201A] {APC} (STJA0001926)

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产品名称：Anti-CD303/CLEC4C antibody [201A] {APC} (STJA0001926)
产品型号：STJA0001926
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CD303/CLEC4C antibody [201A] {APC} (STJA0001926)

产品描述

Host:	Mouse
Applications:	FC
Reactivity:	Human
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-C-type lectin domain family 4 member C is suitable for use in Flow Cytometry research applications.

Clonality:	Monoclonal
Clone ID:	201A
Conjugation:	APC
Isotype:	IgG2ak
Formulation:	PBS with 0.05% Proclin300, 1% BSA
Storage Instruction:	Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.

Gene Symbol:	CLEC4C
Gene ID:	170482
Uniprot ID:	CLC4C_HUMAN

Tissue Specificity	Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha.
Function	Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
Protein Name	C-Type Lectin Domain Family 4 Member C Blood Dendritic Cell Antigen 2 Bdca-2 C-Type Lectin Superfamily Member 7 Dendritic Lectin Cd Antigen Cd303
Database Links	Reactome: R-HSA-5621480 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein
Alternative Antibody Names	Anti-C-Type Lectin Domain Family 4 Member C antibody Anti-Blood Dendritic Cell Antigen 2 antibody Anti-Bdca-2 antibody Anti-C-Type Lectin Superfamily Member 7 antibody Anti-Dendritic Lectin antibody Anti-Cd Antigen Cd303 antibody Anti-CLEC4C antibody Anti-BDCA2 antibody Anti-CLECSF11 antibody Anti-CLECSF7 antibody Anti-DLEC antibody Anti-HECL antibody Anti-UNQ9361 antibody Anti-PRO34150 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CD303/CLEC4C antibody [201A] {APC} (STJA0001926)