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Human MX1 (Myxovirus Resistance 1) Sandwich ELISA Kit Ready-To-Use (STJE0017187)

Human MX1 (Myxovirus Resistance 1) Sandwich ELISA Kit Ready-To-Use (STJE0017187)
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  • 产品名称:Human MX1 (Myxovirus Resistance 1) Sandwich ELISA Kit Ready-To-Use (STJE0017187)
  • 产品型号:STJE0017187
  • 产品展商:ST john's laboratory
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简单介绍
Human MX1 (Myxovirus Resistance 1) Sandwich ELISA Kit Ready-To-Use (STJE0017187)
产品描述
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.27ng/mL
Detection Limit: 0.781-50ng/mL
Short Description: This MX1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: MX1
Gene ID: 4599
Uniprot ID: MX1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity
Post Translational Modifications ISGylated.
Function Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.
Protein Name Interferon-Induced Gtp-Binding Protein Mx1
Interferon-Induced Protein P78
Ifi-78k
Interferon-Regulated Resistance Gtp-Binding Protein Mxa
Myxoma Resistance Protein 1
Myxovirus Resistance Protein 1 Cleaved Into - Interferon-Induced Gtp-Binding Protein Mx1 - N-Terminally Processed
Database Links Reactome: R-HSA-1169408
Reactome: R-HSA-909733
Cellular Localisation Cytoplasm
Endoplasmic Reticulum Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Perinuclear Region
Binds Preferentially To Negatively Charged Phospholipids
Colocalizes With Cchfv Protein N In The Perinuclear Region
Isoform 2: Cytoplasm
Nucleus
Translocates Into The Nuclei Of Hsv-1 Infected Cells
Alternative ELISA Names Interferon-Induced Gtp-Binding Protein Mx1 ELISA kit
Interferon-Induced Protein P78 ELISA kit
Ifi-78k ELISA kit
Interferon-Regulated Resistance Gtp-Binding Protein Mxa ELISA kit
Myxoma Resistance Protein 1 ELISA kit
Myxovirus Resistance Protein 1 Cleaved Into - Interferon-Induced Gtp-Binding Protein Mx1 - N-Terminally Processed ELISA kit
MX1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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