Anti-CD32/FCGR2B antibody [IV-3] (STJA0001500) STJA0001500 上海玉博生物科技有限公司

Anti-CD32/FCGR2B antibody [IV-3] (STJA0001500)

简单介绍

Anti-CD32/FCGR2B antibody [IV-3] (STJA0001500)

产品描述

Host:	Mouse
Applications:	FC
Reactivity:	Human
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-Low affinity immunoglobulin gamma Fc region receptor II-b is suitable for use in Flow Cytometry research applications.

Clonality:	Monoclonal
Clone ID:	IV-3
Conjugation:	Unconjugated
Isotype:	IgG2bk
Formulation:	PBS with 0.05% Proclin300
Concentration:	0.5 mg/mL
Storage Instruction:	Store at 2-8°C. Do not freeze this product.

Tissue Specificity	Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.
Post Translational Modifications	Phosphorylated by the SRC-type Tyr-kinases LYN and BLK.
Function	Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Protein Name	Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B Igg Fc Receptor Ii-B Cdw32 Fc-Gamma Rii-B Fc-Gamma-Riib Fcrii-B Cd Antigen Cd32
Database Links	Reactome: R-HSA-198933
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B antibody Anti-Igg Fc Receptor Ii-B antibody Anti-Cdw32 antibody Anti-Fc-Gamma Rii-B antibody Anti-Fc-Gamma-Riib antibody Anti-Fcrii-B antibody Anti-Cd Antigen Cd32 antibody Anti-FCGR2B antibody Anti-CD32 antibody Anti-FCG2 antibody Anti-IGFR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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